My main headphones/headset is the Bose Quietcomfort 35 ii, they are Bluetooth connected and noise-cancelling.
I use them at home for quality listening at my desktop and when I travel (airplanes, for the noise-cancelling).
I can comfortably wear them for some hours, but then I have to take them of, same as for any headphones I have tried.
Noise-cancelling is good and the sound is great to me even at lower volumes and with classical music. I am currently listening to Rachmaninov's piano concertos at a fairly low volume and enjoy it.
I just want them to correct the spelling of my name! It is "Bosse" not "Bose"!
My headphones!
For other use when I am out and about I recently bought some in ear buds, the Jabra Elite 85T, they are mostly used with my phone as headset and to play music on the go.
They also are noise-cancelling, they come with a nice app that helps you find the right "Eargels" (aka Ear-tips or something, the things you put into your ear) for your ears and then even can try to adapt the sound to your hearing.
When I put them in I can hardly feel that they are there but they seem to sit securely.
Earlier headphones, first was AKG K240 bought in the 70's, still have them but they need some TLC to be used again.
Then I have had some Sennheiser headphones with noise-cancelling first ones was small on-ear type and really worked quit well (PXC 250 IIRC).
(I was flying home from a holiday on Canary Islands and in the row behind me was some women and a baby, I think the baby didn't like the noise in the air-craft and I didn't like the sound of it crying or yelling, what ever it was, so I talked to the women and suggested they let the baby use my headphones without any music or anything but with the noise-cancelling turned on, they accepted to try and the rest of the flight it was just air-craft noise no yelling baby! Well worth it to me!)
Then I got another Sennheiser noise cancelling headphone the PXC 450, the sound is still great and they are comfortable, the noise cancelling worked great almost until the warranty went out, then it stopped working, sent them in for repair and was told the battery had leaked! Hmm, don't think so as I had just used Duracell batteries and I have never seen those leak. I think I paid for the repair and got them back working, but a couple of years later the same problem occurred so I just stopped putting a battery in and used them as plain headphones at home.
I used them with the Cambridge Audio DacMagic XS on my PC, worked great!