For most applications I've gone back to my old "holy trinity", or as near as dammit. My "base set" these days is my XPro2 with 23, 35 and 50mm f2s. Then if I need speed I swap out either the 35mm F2 for the 1.4 or the 50mm F2 for the 1.2. If I need Macro I swap the Fujinon 50mm for the Zeiss 50mm. Wide? Add the 14mm. Tele? Add the 50-230mm or the 100-400mm. Flexibility? The 18-135mm. Single lens? The 18-55mm or if space is at a real premium, the 27mm. That's why I love the X-System; one mount, many options.